Measurement of cognition is critical for diagnosis, monitoring disease progression, and conducting clinical trials in Alzheimer’s disease (AD). Until recently, most measures used in AD research have been designed to evaluate later stages of the disease. The AD field is moving toward much earlier diagnosis and thus, more sensitive measures that assess different cognitive domains are needed. The Division of Neuroscience, and the Division of Behavioral and Social Research, NIA, co-sponsored an exploratory meeting to address these issues, with the purpose of : (1) exploring a range of computerized cognitive assessments and determining gaps and opportunities for further development with respect to understanding the earliest stages of AD and (2) evaluating novel methods and domains (e.g., spatial orientation, prospective memory, etc.) for assessing cognition and looking at the sensitivity/utility of methods and domains that have been used in other populations (college students, normal elderly) to determine which individuals are most likely to develop AD or other dementias.
Assessment of cognition in early dementia. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 2011; 7: e60 – e76
Dr. Nina Silverberg